2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. [Nphe1]Nociceptin(1-13)NH2 TFA

[Nphe1]Nociceptin(1-13)NH2 TFA 

目录号: HY-P1320A
产品使用指南

摩尔计算器

[Nphe1]Nociceptin(1-13) NH2 TFA 是一种 Nociceptin/orphanin FQ (NC) 内源性配体，是一种选择性和竞争性的 ociceptin receptor 拮抗剂，不具有激动剂活性。[Nphe1]nociceptin(1-13)NH2 选择性结合重组 nociceptin 受体(pKi=8.4)，拮抗 nociceptin 对 CHO 细胞中 cAMP 积累的抑制作用(pA2=6.0)。[Nphe1]Nociceptin(1-13)NH2 有可能作为一种止痛试剂。

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Custom Peptide Synthesis

[Nphe1]Nociceptin(1-13)NH2 TFA Chemical Structure

[Nphe1]Nociceptin(1-13)NH2 TFA Chemical Structure

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Other Forms of [Nphe1]Nociceptin(1-13)NH2 TFA:

[Nphe1]Nociceptin(1-13)NH2 TFA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

[Nphe1]Nociceptin(1-13)NH2, a novel nociceptin/orphanin FQ (NC) endogenous ligand, is a selective and competitive ociceptin receptor antagonist without any residual agonist activity. [Nphe1]nociceptin(1-13)NH2 binds selectively to recombinant nociceptin receptors (pKi=8.4) and antagonizes the inhibitory effects of nociceptin on cyclic AMP accumulation in CHO cells (pA2=6.0). [Nphe1]Nociceptin(1-13)NH2 has the potential to act as an analgesic agent[1].

体外研究
(In Vitro)

[Nphe1]nociceptin(1-13)NH2 binds selectively to recombinant nociceptin receptors expressed in Chinese hamster ovary (CHO) cells (pKi=8.4) and competitively antagonizes the inhibitory effects of nociceptin on cyclic AMP accumulation in CHO cells (pA2=6.0) .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

[Nphe1]Nociceptin(1-13)NH2 TFA 相关抗体:
分子量

1495.61

Formula

C63H101F3N22O17
Sequence Shortening

Bn-GGGFTGARKSARK-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

[Nphe1]Nociceptin(1-13)NH2 TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Nphe1]Nociceptin(1-13)NH2Opioid Receptoranalgesic agentInhibitorinhibitorinhibit

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