2. Immunology/Inflammation
  3. CD20
  4. Ocaratuzumab

Ocaratuzumab  (Synonyms: AME 133v; LY 2469298; Humanized Anti-MS4A1 Recombinant Antibody)

目录号: HY-P99308 纯度: 95.00%
COA

摩尔计算器

Ocaratuzumab (AME 133v)，一种 Fc 工程抗体，是人源化的 IgG1 抗 CD20 单克隆抗体，Kd 值为 ~100 pM。Ocaratuzumab 表现出更有效的抗体依赖性细胞介导的细胞毒性 (ADCC)。

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Ocaratuzumab Chemical Structure

Ocaratuzumab Chemical Structure

CAS No. : 1169956-08-4

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规格 价格 是否有货 数量
1 mg ￥3500
In-stock
5 mg ￥9100
In-stock
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Customer Review

Ocaratuzumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ocaratuzumab (AME 133v) is an Fc-engineered humanized IgG1 anti-CD20 monoclonal antibody, with a Kd of ~100 pM. Ocaratuzumab exhibits more effective antibody-dependent cell-mediated cytotoxicity (ADCC)[1][2].

IC50 & Target

Kd: ~100 pM (CD20)[1]
体外研究
(In Vitro)

AME-133v (0.027-20 μg/mL) concentration-dependently inhibits the binding of biotinylated Rituximab to CD20 in SKW6.4 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Ocaratuzumab 相关抗体:
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ocaratuzumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ocaratuzumab1169956-08-4AME 133v LY 2469298 Humanized Anti-MS4A1 Recombinant AntibodyLY2469298LY 2469298LY-2469298CD20Inhibitorinhibitorinhibit

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