2. Peptides
  3. p60c-src Substrate

p60c-src Substrate 是一种高效特异性的 p60c-src 蛋白酪氨酸激酶 (PTK) 的底物。p60c-src Substrate 可用于合成嵌合支化多肽。

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Custom Peptide Synthesis

p60c-src Substrate Chemical Structure

p60c-src Substrate Chemical Structure

CAS No. : 165190-42-1

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p60c-src Substrate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

p60c-src Substrate is an efficient and specific substrate for p60c-src protein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides[1][2].

体外研究
(In Vitro)

p60c-src Substrate (0-200 μM) can be used as peptide substrate[1].
(PhPP)-peptide conjugates were synthesized using PhPP as an ATP mimic and p60c-src Substrate (YIYGSFK) as a peptide substrate to improve the inhibitory potency against active c-Src kinase[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

p60c-src Substrate 相关抗体:
分子量

876.99

Formula

C44H60N8O11
CAS 号
Sequence Shortening

YIYGSFK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

p60c-src Substrate165190-42-1Otherschimeric branched peptidespeptidesubstratec-Srctyrosine kinasePTKInhibitorinhibitorinhibit

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产品名称：
p60c-src Substrate
目录号：
HY-P3743
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