2. Peptides
  3. PAMP-12(human, porcine)

PAMP-12(human, porcine) 

目录号: HY-P2198 纯度: 98.68%
COA 产品使用指南

摩尔计算器

PAMP-12(human, porcine) 是免疫反应性 (ir)-PAMP 的一种主要成分，由肾上腺髓质素前体加工而成，是一种有效的降压肽，可参与心血管方面的调控。

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Custom Peptide Synthesis

PAMP-12(human, porcine) Chemical Structure

PAMP-12(human, porcine) Chemical Structure

CAS No. : 196305-05-2

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥1200
In-stock
5 mg ￥3600
In-stock
10 mg ￥5580
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of PAMP-12(human, porcine):

PAMP-12(human, porcine) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, is processed from the adrenomedullin precursor, is a potent hypotensive peptide and participates in cardiovascular control[1].

体外研究
(In Vitro)

PAMP-12 (human, porcine) is the PAMP[9-20] with a C-terminal amide structure. Intravenous injections of PAMP-12 in anesthetized rats show a significant hypotensive effect in a dose-dependent fashion[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PAMP-12(human, porcine) 相关抗体:
分子量

1618.93

Formula

C77H119N25O14
CAS 号
性状

固体

颜色

White to off-white

Sequence Shortening

FRKKWNKWALSR-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PAMP-12(human, porcine)196305-05-2OthersimmunoreactivePAMPadrenomedullinprecursorhypotensivepeptidecardiovascularInhibitorinhibitorinhibit

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产品名称：
PAMP-12(human, porcine)
目录号：
HY-P2198
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