1. Cytoskeleton
  2. Gap Junction Protein
  3. Peptide5

Peptide5 是 connexin 43 的模拟肽,减少动物脊髓损伤后肿胀、星形胶质细胞增生和神经元细胞死亡。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

Peptide5 Chemical Structure

Peptide5 Chemical Structure

CAS No. : 916977-43-0

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥1400
In-stock
5 mg ¥3500
In-stock
10 mg ¥5200
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Peptide5:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Peptide5, a connexin 43 mimetic peptide, reduce animals swelling, astrogliosis, and neuronal cell death after spinal cord injury[1]

体外研究
(In Vitro)

Peptide5, significantly reduces the degree of spinal cord injury (SCI) in a rodent ex vivo model. Peptide5 produces the more significant reduction in swelling and is analyzed further. Treatment with peptide5 reduced both the level of Cx43 and the number of glial fibrillary acidic protein (GFAP)-positive astrocytes, and at the same time reduces the loss of NeuN- and SMI-32–positive neurons in a concentration- and time-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Peptide5 is could be used to treat traumatic spinal cord injured rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1395.58

Formula

C60H98N16O20S

CAS 号
性状

固体

颜色

White to off-white

Sequence Shortening

VDCFLSRPTEKT

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验: 

DMSO 中的溶解度 : 100 mg/mL (71.65 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.7165 mL 3.5827 mL 7.1655 mL
5 mM 0.1433 mL 0.7165 mL 1.4331 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7165 mL 3.5827 mL 7.1655 mL 17.9137 mL
5 mM 0.1433 mL 0.7165 mL 1.4331 mL 3.5827 mL
10 mM 0.0717 mL 0.3583 mL 0.7165 mL 1.7914 mL
15 mM 0.0478 mL 0.2388 mL 0.4777 mL 1.1942 mL
20 mM 0.0358 mL 0.1791 mL 0.3583 mL 0.8957 mL
25 mM 0.0287 mL 0.1433 mL 0.2866 mL 0.7165 mL
30 mM 0.0239 mL 0.1194 mL 0.2388 mL 0.5971 mL
40 mM 0.0179 mL 0.0896 mL 0.1791 mL 0.4478 mL
50 mM 0.0143 mL 0.0717 mL 0.1433 mL 0.3583 mL
60 mM 0.0119 mL 0.0597 mL 0.1194 mL 0.2986 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
Peptide5
目录号:
HY-P2275
需求量: