2. Anti-infection
  3. Antibiotic Bacterial
  4. Polymyxin B2

Polymyxin B2  (Synonyms: 多粘菌素 B2)

目录号: HY-A0248B 纯度: 97.25%
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Polymyxin B2 是一种多肽类抗生素，具有抗细菌活性，特别是对抗革兰氏阴性细菌。Polymyxin B2 通过与细菌细胞膜上的脂多糖分子结合，破坏细胞膜的完整性，导致细胞内容物泄漏，从而杀死细菌。Polymyxin B2 可用于抗生素开发和治疗耐药菌株的研究。

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Polymyxin B2

Polymyxin B2 Chemical Structure

CAS No. : 34503-87-2

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5 mg ￥2070
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10 mg ￥3330
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Other Forms of Polymyxin B2:

Polymyxin B2 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 can be used in antibiotic development and treatment of drug-resistant strains[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Vero CC50
159 μg/mL
Compound: Polymyxin B2
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
[PMID: 29412662]
分子量

1189.45

Formula

C55H96N16O13
CAS 号
性状

固体

颜色

White to off-white

中文名称

多粘菌素 B2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

Polymyxin B2 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Polymyxin B234503-87-2多粘菌素 B2Polymyxin B 2Polymyxin B-2AntibioticBacterialGram-negative bacteriaantibioticslipopolysaccharidesdrug-resistant strainsInhibitorinhibitorinhibit

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