2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 根据产品特点分类
  6. 抗生素化合物库
抗生素化合物库 - Antibiotics Library

Cat. No.: HY-L067

抗生素可以杀死或抑制细菌的生长，是一类用于治疗和预防细菌感染的抗菌产品。虽然抗生素的主要作用目标是细菌，但有些抗生素也会对真菌和原生动物产生抑制作用。然而，抗生素很少对病毒起作用。抗生素的主要作用机制包括四种：抑制细胞壁合成、抑制核酸代谢及修复、抑制蛋白质合成或破坏膜。许多抗生素靶向的细胞功能在快速增殖细胞中最为活跃。由于这些功能在原核细菌及真核哺乳动物细胞之间经常有重叠，所以一些抗生素也被发现具有很好的抗肿瘤效果。

MCE 收录了 633 种抗生素，包括青霉素类、头孢菌素类、四环素类、大环内酯类等多种类型，是开发抗菌及抗肿瘤药物的有效工具。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 抗生素化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，609 个产品以 10 mM 浓度提供，15 个产品以 2 mM 浓度提供，9 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 633 antibiotics for high throughput screening (HTS) and high content screening (HCS).

•   The antibiotics in the library contain penicillins, cephalosporins, tetracyclines, macrolides, etc.

•   A useful tool for the discovery of anti-bacterial and anti-cancer drugs.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   Validated NMR and HPLC to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 633 antibiotics supplied as pre-dissolved Solutions or Solid
Solution: 609 compounds supplied in 10 mM solution, 15 compounds supplied in 2 mM solution, 9 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice

化合物库组成

Composition

HSV (11)

HIV (8)

MMP (6)

PKC (5)

STAT (4)

FKBP (3)

HCV (3)

HSP (3)

Wnt (3)

CMV (2)

COX (2)

HBV (2)

PDI (2)

PI3K (2)

PKA (2)

PPAR (2)

AMPK (1)

BCRP (1)

CaMK (1)

CDK (1)

ERK (1)

IKK (1)

IRE1 (1)

JNK (1)

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定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Antibiotics Library
    目录号：
    HY-L067
    需求量：

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