1. Apoptosis
  2. Bcl-2 Family
  3. PUMA BH3 TFA

PUMA BH3 TFA 是一种 p53 正向凋亡调控因子 (PUMA) 含 BH3 结构域的多肽,作为 Bak 的直接激活剂,Kd 值为 26 nM。

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Custom Peptide Synthesis

PUMA BH3 TFA Chemical Structure

PUMA BH3 TFA Chemical Structure

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PUMA BH3 TFA 的其他形式现货产品:

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查看 Bcl-2 Family 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PUMA BH3 TFA is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM[1].

IC50 & Target[1]

Bak

26 nM (Kd)

体外研究
(In Vitro)

PUMA BH3 TFA 是 p53 上调的细胞凋亡调节剂 (PUMA) BH3 结构域肽,可作为 Bak 的直接激活剂,Kd 为 26 nM。 PUMA BH3 TFA 在典型的 BH3 结合沟中结合 Bak,并激活 Bak[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

2384.63 (free base)

Formula

C100H162N34O32S.xC2HF3O2

Sequence

Ac-Glu-Gln-Trp-Ala-Arg-Glu-Ile-Gly-Ala-Gln-Leu-Arg-Arg-Met-Ala-Asp-Asp-Leu-Asn-Ala-NH2

Sequence Shortening

Ac-EQWAREIGAQLRRMADDLNA-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

PUMA BH3 TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PUMA BH3 TFA
目录号:
HY-P1562A
需求量: