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QM385 

目录号: HY-114388
产品使用指南

QM385 是一种有效的降血糖素还原酶 (SPR) 抑制剂,IC50 值为 1.49 nM,并以纳摩尔效力和良好的口服生物利用度阻止 T 细胞增殖和自身免疫。

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QM385 Chemical Structure

QM385 Chemical Structure

CAS No. : 2296727-52-9

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Description

QM385 is a potent sepiapterin reductase (SPR) inhibitor with an IC50 of 1.49 nM, which blocks T-cell proliferation and autoimmunity at nanomolar potency and with good oral bioavailability[1].

IC50 & Target

IC50: 1.49 nM (Sepiapterin reductase)[1]

In Vitro

QM385 effectively inhibits the proliferation of human CD4+ T cells at low doses[1].

Molecular Weight

408.38

Formula

C₁₈H₁₉F₃N₆O₂

CAS No.

2296727-52-9

SMILES

O=C1NC(N2N=CC(C(N3CCC(CC(F)(F)F)CC3)=O)=C2C)=NN4C1=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
QM385
目录号:
HY-114388
需求量:

QM385

Cat. No.: HY-114388