Animal-Free FGF-17 蛋白, Human (His)

FGF-17 Protein plays a crucial role in embryonic development, serving as a signaling molecule for brain induction and patterning. Its presence is vital for normal brain development, emphasizing its significance in shaping embryogenesis intricacies. FGF-17 interacts with FGFR3 and FGFR4, underscoring its involvement in signaling cascades that precisely orchestrate developmental events in the embryonic brain. Animal-Free FGF-17 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-17 protein, expressed by E. coli, with N-His labeled tag. The total length of Animal-Free FGF-17 Protein, Human (His) is 194 a.a., with molecular weight of ~23.32 kDa.

FGF-17 蛋白在调节胚胎发育中发挥着至关重要的作用，并在胚胎大脑的诱导和模式形成中充当信号分子。它的存在对于正常的大脑发育至关重要，强调了它在塑造复杂的胚胎发生过程中的重要性。值得注意的是，FGF-17 与 FGFR3 和 FGFR4 相互作用，强调其参与复杂的信号级联反应，有助于胚胎大脑中发育事件的精确协调。

Measure by its ability to induce 3T3 cells proliferation. The ED₅₀ for this effect is <5 ng/mL. The specific activity of recombinant human FGF-17 is > 2 x 10⁵ IU/mg.

Human

E. coli

N-His

O60258 (T23-T216)

8822  [NCBI]

TQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAEKQKQFEFVGSAPTRRTKRTRRPQPLT

Approximately 23.32 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 1X PBS, pH 8.0.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.