1. 重组蛋白
  2. CD Antigens
  3. B Cell CD Proteins Macrophage CD Proteins Monocyte CD Proteins Platelet CD Proteins Erythrocyte CD Proteins Dendritic Cell CD Proteins
  4. CD147
  5. Basigin/CD147 蛋白, Human (HEK293)

Basigin/CD147 蛋白, Human (HEK293)

目录号: HY-P74388
COA 产品使用指南

Basigin/BSG 蛋白对于视网膜成熟和发育至关重要,并且作为 NXNL1 的视网膜细胞受体发挥作用,促进视网膜锥体感光细胞的存活。Basigin/CD147 蛋白, Human (HEK293) 是重组的 Basigin/CD147 蛋白,由 HEK293 表达,不带标签。Basigin/CD147 蛋白, Human (HEK293) 全长 184 个氨基酸,分子量为 35-38 kDa。

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1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
10 μg ¥1150 In-stock
50 μg ¥2950 In-stock
100 μg   询价  

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描述

Basigin/BSG proteins are critical for retinal maturation and development and function as retinal cell receptors for NXNL1, promoting the survival of retinal cone photoreceptors. Basigin/CD147 Protein, Human (HEK293) is the recombinant human-derived Basigin/CD147 protein, expressed by HEK293 , with tag free. The total length of Basigin/CD147 Protein, Human (HEK293) is 184 a.a., with molecular weight of 35-38 kDa.

研究背景

Basigin/BSG 蛋白对于视网膜的正常成熟和发育至关重要,作为 NXNL1 的关键细胞表面受体,并在 NXNL1 介导的视网膜锥光感受器的存活中发挥关键作用。Basigin/BSG 与葡萄糖转运蛋白 SLC16A1/GLUT1 和 NXNL1 合作,通过促进有氧糖酵解和加速葡萄糖进入光感受器来促进视网膜锥体的存活。此外,它还是各种细胞系(包括单核细胞)中 IL6 分泌的有效诱导剂。在微生物感染的情况下,Basigin/BSG 作为恶性疟原虫 RH5 的红细胞受体,在恶性疟原虫分离株 3D7 和 Dd2 裂殖子阶段的红细胞侵袭中发挥着不可或缺的作用。这些不同的功能凸显了 Basigin/BSG 在细胞过程和宿主-病原体相互作用中的多方面作用。

种属

Human

表达系统

HEK293

标签

Tag Free

蛋白编号

P35613-2 (A22-H205)

基因 ID

682  [NCBI]

蛋白结构
N-term
Basigin (A22-H205)
Accession # P35613-2
C-term
同用名
Basigin; HT7 antigen; Membrane glycoprotein gp42; Bsg
分子量

35-38 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

溶液.

组分

Supplied as a 0.2 μm filtered solution of 50 mM Tris, 100 mM NaCl, pH 8.0.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

N/A.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Basigin/CD147 Protein, Human (HEK293)
目录号:
HY-P74388
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