CD133/PROM1 蛋白, Rat (HEK293, Fc)

The CD133/PROM1 protein is critical for multiple processes including glomerular epithelial cell differentiation and retinal morphogenesis, showing biased expression in tissues such as lung and kidney. CD133/PROM1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD133/PROM1 protein, expressed by HEK293 , with N-mFc labeled tag. The total length of CD133/PROM1 Protein, Rat (HEK293, Fc) is 254 a.a., with molecular weight of ~70-95 KDa.

CD133/PROM1 蛋白预计具有肌动蛋白结合活性、钙粘蛋白结合活性和胆固醇结合活性。该蛋白质预计参与多种过程，包括肾小球上皮细胞分化、感光细胞维持和相机型眼睛中的视网膜形态发生。CD133 预计位于内质网-高尔基中间室、细胞外外泌体和光感受器外节膜等细胞成分中，预计在顶端质膜、微绒毛和前粒体等细胞成分中具有活性。此外，预计它是质膜的一个组成部分。CD133 用于糖尿病研究，并与锥杆营养不良 12 和色素性视网膜炎 41 等人类疾病有关。值得注意的是，CD133 在组织中表现出偏向表达，在肺、肾和其他八种组织中观察到显着水平的表达，表明其在这些器官中的不同功能作用。

Data is not available.

Rat

HEK293

N-mFc

NP_001103607.1 (N171-Y424)

60357  [NCBI]

NQQTRTRIQRTQKLAESNYRDLRALLTEAPKQIDYILGQYNTTKNKAFSDLDSIDSVLGGRIKGQLKPKVTPVLEEIKAMATAIRQTKDALQNMSSSLKSLRDASTQLSTNLTSVRNSIENSLNSNDCASDPASKICDSLRPQLSNLGSNHNGSQLQSVDRELNTVNDVDRTDLESLVKRGYMSIDEIPNMIQNQTGDVIKDVKKTLDSVSSKVKNMSQSIPVEEVLLQFSHYLNDSNRYIHESLPRVEEYDSY

Approximately 70-95 kDa.

• 
  Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.