1. 重组蛋白
  2. CD Antigens
  3. Stem Cell CD Proteins Epithelial cell CD Proteins Cell Adhesion-related CD Proteins
  4. MUC-24/CD164
  5. CD164 蛋白, Human (HEK293, His)

CD164 蛋白, Human (HEK293, His)

目录号: HY-P75617
产品使用指南

CD164是一种唾液酸粘蛋白,可能在造血过程中发挥关键作用,促进CD34(+)细胞粘附,同时负向调节CD34(+)CD38(lo/-)细胞增殖。它通过 CXCL12/CXCR4 轴调节脐带血 CD133+ 细胞迁移,并与前列腺癌转移和骨髓侵袭相关。CD164 蛋白, Human (HEK293, His) 是重组的 CD164 蛋白,由 HEK293 表达,带有 C-His 标签。CD164 蛋白, Human (HEK293, His) 全长 139 个氨基酸,分子量为 40-110 kDa。

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描述

CD164 is a sialylamucin that may play a key role in the hematopoietic process, promoting CD34(+) cell adhesion while negatively regulating CD34(+)CD38(lo/-) cell proliferation. It regulates cord blood CD133+ cell migration through the CXCL12/CXCR4 axis and is associated with prostate cancer metastasis and bone marrow invasion. CD164 Protein, Human (HEK293, His) is the recombinant human-derived CD164 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD164 Protein, Human (HEK293, His) is 139 a.a., with molecular weight of 40-110 kDa.

研究背景

CD164是一种唾液酸粘蛋白,在造血过程中可能发挥关键作用,促进CD34(+)细胞与基质的粘附,同时负向调节CD34(+)CD38(lo/-)细胞的增殖。该蛋白参与通过 CXCL12/CXCR4 轴调节脐带血 CD133+ 细胞迁移。此外,CD164 与前列腺癌转移和癌细胞浸润到骨髓有关。它通过增强 CXCR4 依赖性细胞运动、促进成肌细胞迁移并促进成肌细胞融合成肌管,对肌生成产生积极影响。该蛋白质以同二聚体(亚型 4)存在,并在这些细胞过程中与 CXCR4 相互作用。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

Q04900 (D24-D162)

基因 ID
蛋白结构
N-term
CD164 (D24-D162)
Accession # Q04900
His
C-term
同用名
Sialomucin core protein 24; MUC-24; Endolyn; MGC-24; CD164
分子量

40-110 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD164 Protein, Human (HEK293, His)
目录号:
HY-P75617
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