1. 重组蛋白
  2. CD Antigens Complement System
  3. B Cell CD Proteins Epithelial cell CD Proteins Complement Receptor
  4. CD21/CR2 Complement Receptor 2
  5. CD21 蛋白, Human (HEK293, His)

CD21 蛋白, Human (HEK293, His)

目录号: HY-P72890
COA 产品使用指南

CD21 蛋白是补体 C3、Epstein-Barr 病毒和 HNRNPU 的受体,可激活 B 淋巴细胞并帮助 Epstein-Barr 病毒进入微生物感染。它与这些配体的结合凸显了它在免疫反应和相互作用、调节 B 细胞激活和宿主防御感染方面的重要作用。CD21 蛋白, Human (HEK293, His) 是重组的 CD21 蛋白,由 HEK293 表达,带有 C-His, C-10*His 标签。CD21 蛋白, Human (HEK293, His) 全长 951 个氨基酸,分子量为 110-120 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
Free Sample   Apply now  
5 μg ¥430 In-stock
10 μg ¥740 In-stock
50 μg ¥2060 In-stock
100 μg ¥3500 In-stock
500 μg ¥9800 In-stock
> 100 μg   询价  

* Please select Quantity before adding items.

注册 MCE会员完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products
  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

CD21 Protein, a receptor for complement C3, Epstein-Barr virus, and HNRNPU, activates B lymphocytes and aids Epstein-Barr virus entry in microbial infection. Its engagement with these ligands highlights its vital role in immune responses and interactions, regulating B-cell activation and host defense against infections. CD21 Protein, Human (HEK293, His) is the recombinant human-derived CD21 protein, expressed by HEK293 , with C-His, C-10*His labeled tag. The total length of CD21 Protein, Human (HEK293, His) is 951 a.a., with molecular weight of 110-120 kDa.

研究背景

CD21 蛋白作为补体 C3、人类 B 细胞和 T 细胞上的 Epstein-Barr 病毒以及 HNRNPU 的受体。它在 B 淋巴细胞的激活中起着至关重要的作用,并在微生物感染期间充当 Epstein-Barr 病毒的受体。CD21 与这些配体的结合强调了其在介导免疫反应以及与病原体和内源性因子相互作用方面的重要性,有助于调节 B 细胞激活和宿主防御感染。

生物活性

Measured by its binding ability in a functional ELISA. Immobilized Human CD21, at 2 μg/mL (100 μl/well) can bind Biotinylated Human Annexin VI/ANXA6, the ED50 for this effect is 378.6 ng/mL.

  • Measured by its binding ability in a functional ELISA. Immobilized Human CD21,at 2 μg/ml (100 μl/well) can bind Biotinylated Human Annexin VI/ANXA6 , the ED50 for this effect is 378.6 ng/mL.
种属

Human

表达系统

HEK293

标签

C-10*His

蛋白编号

P20023-1 (I21-R971)

基因 ID
蛋白结构
N-term
CD21 (I21-R971)
Accession # P20023-1
10*His
C-term
同用名
Complement receptor type 2; Cr2; EBV receptor; CD21; C3DR
氨基酸序列

ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSR

分子量

110-120 kDa

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末

组分

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
CD21 Protein, Human (HEK293, His)
目录号:
HY-P72890
需求量: