2. 重组蛋白
  3. Cytokines and Growth Factors Immune Checkpoint Proteins CD Antigens
  4. TNF Superfamily Stimulatory Immune Checkpoint Molecules T Cell CD Proteins B Cell CD Proteins Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins Epithelial cell CD Proteins Endothelial cell CD Proteins
  5. TNF Receptor Superfamily CD40 GITR/CD357
  6. CD40 蛋白, Rat (HEK293, Fc)

CD40 蛋白, Rat (HEK293, Fc)

目录号: HY-P74296
产品使用指南

CD40，也称为 TNFR5，是一种在特征注释传播所需的保守残基中表现出缺陷的蛋白质。CD40 中缺失的特定残基阻止了与该蛋白质相关的某些功能特征的传播。CD40 蛋白, Rat (HEK293, Fc) 是重组的 CD40 蛋白，由 HEK293 表达，带有 C-hFc 标签。CD40 蛋白, Rat (HEK293, Fc) 全长 193 个氨基酸，分子量约为 ~53 kDa。

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描述

CD40, also known as TNFR5, is a protein that exhibits defects in conserved residues necessary for feature annotation propagation. Specific residues missing in CD40 prevent the propagation of certain functional features associated with this protein. CD40 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD40 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD40 Protein, Rat (HEK293, Fc) is 193 a.a., with molecular weight of ~53 kDa.
研究背景

CD40，也称为 TNFR5，是一种在特征注释传播所必需的保守残基上表现出缺陷的蛋白质。CD40 中缺失的特定残基阻止了与该蛋白质相关的某些功能特征的传播。CD40是肿瘤坏死因子受体（TNFR）超家族的成员，在免疫调节和多种免疫细胞的激活中发挥着至关重要的作用。
种属

Rat
表达系统

HEK293
标签

C-hFc
蛋白编号

Q4QQW2 (M1-R193)
基因 ID

171369  [NCBI]
蛋白结构
N-term
CD40 (M1-R193)
Accession # Q4QQW2
hFc
C-term
同用名
Tumor Necrosis Factor Receptor Superfamily member 5; Bp50; CD40L Receptor; CDw40; TNFRSF5
分子量

Approximately 53 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CD40 Protein, Rat (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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