1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Interleukin & Receptors
  4. IL-16
  5. IL-16 蛋白, Human (His)

IL-16 蛋白, Human (His)

目录号: HY-P73169
产品使用指南

IL-16 蛋白是一种细胞因子,可调节免疫和炎症。它控制 T 细胞和单核细胞等免疫细胞的激活和运动。了解 IL-16 蛋白的功能有助于研究免疫反应并开发炎症和自身免疫性疾病的治疗方法。IL-16 蛋白, Human (His) 是重组的 IL-16 蛋白,由 E. coli 表达,带有 N-His 标签。IL-16 蛋白, Human (His) 全长 129 个氨基酸,分子量约为 ~15.3 kDa。

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描述

IL-16 Protein, a cytokine, regulates immunity and inflammation. It controls the activation and movement of immune cells like T cells and monocytes. Understanding IL-16 Protein's functions helps study immune responses and develop treatments for inflammatory and autoimmune disorders. IL-16 Protein, Human (His) is the recombinant human-derived IL-16 protein, expressed by E. coli , with N-His labeled tag. The total length of IL-16 Protein, Human (His) is 129 a.a., with molecular weight of ~15.3 kDa.

研究背景

IL-16 是一种多功能细胞因子,可引起 CD4+ 淋巴细胞、单核细胞和嗜酸性粒细胞的迁移反应。此外,它还启动 CD4+ T 细胞对 IL-2IL-15 的反应,并诱导 T 淋巴细胞中白细胞介素 2 受体的表达。IL-16 作为 CD4 的配体,在细胞相互作用和免疫调节中发挥着关键作用。除了其免疫调节功能外,IL-16 还可以作为一种支架蛋白,将离子通道锚定在细胞膜上,从而发挥其多种细胞作用。

种属

Human

表达系统

E. coli

标签

N-His

蛋白编号

AAC12732.1 (P2-S130)

基因 ID
蛋白结构
N-term
His
IL-16 (P2-S130)
Accession # Q14005
C-term
同用名
Pro-interleukin-16; Interleukin-16; IL-16; LCF
分子量

Approximately 15.3 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

IL-16 Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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