1. 重组蛋白
  2. Enzymes & Regulators
  3. Protease Inhibitors
  4. Serpin (Protease Inhibitor)
  5. PAI-1
  6. Serpin E1 蛋白, Rat (HEK293, Fc)

Serpin E1 蛋白, Rat (HEK293, Fc)

目录号: HY-P73336
产品使用指南

Serpin E1 是一种丝氨酸蛋白酶抑制剂,可调节 TMPRSS7 并抑制组织型纤溶酶原激活剂 (PLAT) 和尿激酶型纤溶酶原激活剂 (PLAU)。它可以显着下调纤维蛋白溶解并控制血栓降解。Serpin E1 蛋白, Rat (HEK293, Fc) 是重组的 丝氨酸蛋白酶抑制剂 E1 蛋白,由 HEK293 表达,带有 C-hFc 标签。Serpin E1 蛋白, Rat (HEK293, Fc) 全长 402 个氨基酸,分子量约为 ~70 kDa。

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描述

Serpin E1 is a serine protease inhibitor that regulates TMPRSS7 and inhibits tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). It can significantly downregulate fibrinolysis and control thrombus degradation. Serpin E1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Serpin E1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Serpin E1 Protein, Rat (HEK293, Fc) is 402 a.a., with molecular weight of ~70 kDa.

研究背景

SLAMF6 蛋白是一种自配体受体,属于信号淋巴细胞激活分子 (SLAM) 家族。它参与调节各种免疫细胞的激活和分化,在先天性和适应性免疫反应中发挥作用。SLAMF6 的活性受细胞质接头蛋白(即 SH2D1A/SAP 和/或 SH2D1B/EAT-2)的存在或不存在调节。

种属

Rat

表达系统

HEK293

标签

C-hFc

蛋白编号

P20961 (M1-P402)

基因 ID
蛋白结构
N-term
Serpin E1 (M1-P402)
Accession # P20961
hFc
C-term
同用名
Plasminogen activator inhibitor 1; PAI-1; Serpin E1; Serpine1; Planh1
分子量

Approximately 70 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Serpin E1 Protein, Rat (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Serpin E1 Protein, Rat (HEK293, Fc)
目录号:
HY-P73336
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