2. Peptides
  3. Renin FRET Substrate I

Renin FRET Substrate I 是人肾素的底物。Renin FRET Substrate I 可以作为整合人血管紧张素原 N 端肽段中出现的肾素裂解位点。

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Custom Peptide Synthesis

Renin FRET Substrate I Chemical Structure

Renin FRET Substrate I Chemical Structure

CAS No. : 142988-22-5

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Renin FRET Substrate I 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Renin FRET Substrate I is a substrate of human renin. Renin FRET Substrate I is designed to incorporate the renin cleavage site that occurs in the N-terminal peptide of human angiotensinogen[1].

体外研究
(In Vitro)

Cleavage of Renin FRET Substrate I occurs specifically at the Leu-Val bond and corresponds to the renin cleavage site of angiotensinogen[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Renin FRET Substrate I 相关抗体:
分子量

1798.12

Formula

C90H120N22O16S
CAS 号
Sequence

DABCYL-γ-{Abu}-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Glu-Asp-Ala-Asn-Ser
Sequence Shortening

DABCYL-γ-{Abu}-IHPFHLVIHT-EDANS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Renin FRET Substrate I142988-22-5OthersInhibitorinhibitorinhibit

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产品名称：
Renin FRET Substrate I
目录号：
HY-P2492
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