2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation
  3. Antibody-Drug Conjugates (ADCs) TROP2
  4. Sacituzumab tirumotecan

Sacituzumab tirumotecan  (Synonyms: SKB264; MK-2870)

目录号: HY-164789 纯度: 99.63%
COA 产品使用指南 技术支持

Sacituzumab tirumotecan (SKB264/MK-2870) 是一种 TROP2 ADC。Sacituzumab tirumotecan 的内化和抗肿瘤活性在 EGFR 突变的肿瘤细胞系内得到增强。Sacituzumab tirumotecan 可用于三阴性乳腺癌 (TNBC) 和非小细胞肺癌 (NSCLC) 等癌症的研究。

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Sacituzumab tirumotecan

Sacituzumab tirumotecan Chemical Structure

CAS No. : 2768350-77-0

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规格 价格 是否有货 数量
1 mg ￥4500
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Sacituzumab tirumotecan 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sacituzumab tirumotecan (SKB264/MK-2870) is a TROP2 ADC. The internalization and anti-tumor activity of Sacituzumab tirumotecan are enhanced in tumor cell lines with EGFR mutations. Sacituzumab tirumotecan can be used in the research of triple negative breast cancer (TNBC), non small cell lung cancer (NSCLC) and other cancers[1][2].

Clinical Trial
分子量

157907 (average)

CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

-80°C, protect from light
纯度 & 产品资料

纯度: 99.63%

COA (266 KB) Others (171 KB) SEC-HPLC (131 KB)

产品使用指南 (1538 KB)
参考文献

Sacituzumab tirumotecan 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sacituzumab tirumotecan2768350-77-0SKB264 MK-2870SKB 264SKB-264MK2870MK 2870MK-2870Antibody-Drug Conjugates (ADCs)TROP2Antibody-Drug ConjugatesEGP-1M1S1GA733-1ADCcancerEGFRTNBCNSCLCInhibitorinhibitorinhibit

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