2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. ST-1006 Maleate

ST-1006 maleate 是一种有效的组胺 H4 受体 (histamine H4 receptor) 激动剂，其 pKi 值为 7.94。ST-1006 maleate 具有抗炎作用。

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ST-1006 Maleate Chemical Structure

ST-1006 Maleate Chemical Structure

CAS No. : 1196994-12-3

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规格 是否有货
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ST-1006 Maleate 的其他形式现货产品:

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ST-1006 Maleate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ST-1006 maleate is a potent histamine H4 receptor agonist with a pKi value of 7.94. ST-1006 maleate has anti-inflammatory effect[1][2].

体外研究
(In Vitro)

ST-1006 (10 μM) maleate is a potent inducer of basophil migration and induces migration of basophils[2].
ST-1006 (0-100 μM) maleate suppress FceRImediated basophil activation and reduces the CD63 and CD203c expression levels on FceRI-activated basophils[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

ST-1006 Maleate 相关抗体:
体内研究
(In Vivo)

ST-1006 (1-100 mg/kg; s.c.; Male CD-1 mice) maleate has anti-inflammatory effect and displays an antipruritic effect[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male CD-1 mice with pruritus (8-10 weeks and 25-30 g)[1]
Dosage: 1-100 mg/kg
Administration: Subcutaneous injection
Result: Had an antipruritic effect at the non-anti-inflammatory dose of 30 mg/kg.
分子量

599.42

Formula

C24H28Cl2N6O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ST-1006 Maleate 相关分类

  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ST-10061196994-12-3ST1006ST 1006Histamine Receptoranti-inflammatoryantipruriticbasophilsFceRIInhibitorinhibitorinhibit

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ST-1006 Maleate
目录号：
HY-120541A
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