2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. UBP141

UBP141 是一种 GluN2C/2D (NR2C/2D) 偏好受体拮抗剂，对于 NMDA 受体亚型 GluN2C，2D，2A 和 2B 的 Kd 值为分别 2.8，4.2，14.2 和 19.3 μM。UBP141 可诱导 WT 小鼠出现严重的运动障碍。

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UBP141 Chemical Structure

UBP141 Chemical Structure

CAS No. : 344768-30-5

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UBP141 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

UBP141 is a GluN2C/2D (NR2C/2D)-preferring receptor antagonist, with Kds of 2.8, 4.2, 14.2, and 19.3 μM for NMDA receptor subtypes: GluN2C, 2D, 2A, and 2B, respectively. UBP141 can induce potent motor impairment in WT mice[1][2].

分子量

378.38

Formula

C21H18N2O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

UBP141 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UBP141344768-30-5UBP 141UBP-141iGluRIonotropic glutamate receptorsInhibitorinhibitorinhibit

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