2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. UFP-101

UFP-101 是一种有效、选择性和竞争性的 NOP 受体拮抗剂，pKi 为 10.24。UFP-101 对 δ、μ 和 κ 类阿片受体的选择性大于 3000 倍。UFP-101 具有抗抑郁药样作用。

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Custom Peptide Synthesis

UFP-101 Chemical Structure

UFP-101 Chemical Structure

CAS No. : 849024-68-6

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规格 是否有货
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UFP-101 的其他形式现货产品:

Customer Review

Other Forms of UFP-101:

UFP-101 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

UFP-101 is a potent, selective, and competitive antagonist of the NOP receptor, with a pKi of 10.24. UFP-101 displays >3000-fold selectivity over δ, μ and κ opioid receptors. UFP-101 shows antidepressant-like effect[1][2].

IC50 & Target

NOP Receptor/ORL1

 

体内研究
(In Vivo)

UFP-101 elicits a pronounced acute and dosedependent antidepressant-like effect in mice submitted to the forced swimming test (FST)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1908.17

Formula

C82H138N32O21
CAS 号
Sequence Shortening

{Bn}-GGGFTGARKSARKRKNQ-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

UFP-101 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UFP-101849024-68-6UFP101UFP 101Opioid Receptorselectivecompetitiveantidepressantforcedswimmingtestligand,Inhibitorinhibitorinhibit

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目录号：
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