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  3. Viridicatumtoxin

Viridicatumtoxin 是从绿色青霉菌中提取的一种新型霉菌毒素,在大鼠体内的 LD50 为 122.4 mg/kg。

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Viridicatumtoxin Chemical Structure

Viridicatumtoxin Chemical Structure

CAS No. : 39277-41-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Viridicatumtoxin is a new mycotoxin extracted from Penicillium viridicatum with a LD50 of 122.4 mg/kg in rats.

体内研究
(In Vivo)

Viridicatumtoxin (60-400 mg/kg; i.p., p.o., s.c; ICR mice, Sprague-Dawley rats and mature Wistar rats (4/5 weeks; 16-20 g/140-150 g)) has no signs of toxicity with p.o. administration. As the dosage increasing (i.p. and p.o.), hepatocytes starts to have pathological changes and deaths occurrs in both mice and rats. Mice and rats which given the viridicatumtoxin by s.c. has no signs of toxicity and none die, but coagulation necrosis is present at the injection site[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: ICR mice, Sprague-Dawley rats and mature Wistar rats (4/5 weeks; 16-20 g/140-150 g)[2]
Dosage: 60-400 mg/kg
Administration: i.p., p.o., s.c.
Result: Orally with viridicatumtoxin had no signs of toxicity. As the dosage increasing (i.p. and p.o.), hepatocytes started to have pathological changes and deaths occurred in both mice and rats. Mice and rats which given the viridicatumtoxin by s.c. had no signs of toxicity and none died, but coagulation necrosis was present at the injection site.
分子量

565.57

Formula

C30H31NO10

CAS 号
结构分类
初始来源

Penicillium viridicatum Westling

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Viridicatumtoxin 相关分类

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Viridicatumtoxin
目录号:
HY-129208
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