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  3. VU6005806

VU6005806 (Synonyms: AZN-00016130)

目录号: HY-128584
产品使用指南

VU6005806 (AZN-00016130) 是一种有效的毒蕈乙酰胆碱受体亚型 4 (M4) 的正向别构调节剂,对人、大鼠、狗、猴 M4EC50 值分别为 94 nM,28 nM,87 nM 和 68 nM。用于神经疾病的研究。

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VU6005806 Chemical Structure

VU6005806 Chemical Structure

CAS No. : 2180914-37-6

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Description

VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders[1].

IC50 & Target

IC50: 94 nM (Human M4), 28 nM (Rat M4), 87 nM (Dog M4), 68 nM (Cyno M4)[1]

Molecular Weight

439.41

Formula

C₁₇H₁₆F₃N₇O₂S

CAS No.

2180914-37-6

SMILES

NC1=C(C(NC2CN(C3=NC=C(C(F)(F)F)C=N3)C2)=O)SC4=NN=C(OC)C(C)=C41

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
VU6005806
目录号:
HY-128584
需求量:

VU6005806

Cat. No.: HY-128584