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  4. XM462

XM462 是一种二氢神经酰胺去饱和酶抑制剂。 XM462 在体外产生混合型抑制（Ki=2 μM）。 XM462 在体外和培养细胞中均具有二氢神经酰胺去饱和酶抑制作用，IC50 值分别为 8.2 和 0.78 μM。

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XM462 Chemical Structure

XM462 Chemical Structure

CAS No. : 1045857-53-1

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XM462 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

XM462 is a dihydroceramide desaturase inhibitor. XM462 produced a mixed-type inhibition (Ki=2 μM) in vitro. XM462 has dihydroceramide desaturase inhibition both in vitro and in cultured cells with IC50 values of 8.2 and 0.78 μM, respectively. XM462 can be used for the research of tumor[1][2].

IC50 & Target

IC50: 8.2 μM (dihydroceramide desaturase in vitro); 0.78 μM (dihydroceramide desaturase in cultured cells)[1].
分子量

445.74

Formula

C25H51NO3S
CAS 号
非同位 CAS

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

XM462 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XM4621045857-53-1XM 462XM-462Othersdihydroceramide desaturasetumorInhibitorinhibitorinhibit

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