2. Metabolic Enzyme/Protease
  3. Angiotensin-converting Enzyme (ACE)
  4. Rentiapril racemate

Rentiapril racemate  (Synonyms: SA-446 racemate)

目录号: HY-U00074 纯度: 98.96%
COA 产品使用指南

摩尔计算器

Rentiapril racemate (SA-446 racemate) 是 Rentiapril 的外消旋体。Rentiapril 是一种血管紧张素转换酶 (ACE) 抑制剂。

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Rentiapril racemate Chemical Structure

Rentiapril racemate Chemical Structure

CAS No. : 72679-47-1

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规格 价格 是否有货 数量
1 mg ￥909
In-stock
5 mg ￥2000
In-stock
10 mg ￥3400
In-stock
25 mg ￥7100
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Other Forms of Rentiapril racemate:

Rentiapril racemate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril. Rentiapril is an angiotensin converting enzyme (ACE) inhibitor.

IC50 & Target

Angiotensin converting enzyme (ACE)[1]
体内研究
(In Vivo)

A three-months toxicity study of an angiotensin converting enzyme (ACE) inhibitor, Rentiapril (CAS 80830-42-8), is performed in Sprague-Dawley rats by oral administration. The dose levels of 0, 30, 125, 500 and 1000 mg/kg are tested in both sexes, in which each experimental group comprised 10 rats. Another ACE inhibitor, captopril, is used as a reference compound. Rentiapril at the highest dose of 1000 mg/kg causes low food consumption and death of some animals with signs of bloody feces and anemia. In males and females receiving 500 and 1000 mg/kg, there are low body weight gain, increases in water intake, urine volume and serum BUN level, and decreases in levels of various erythrocytic parameters. Kidney weight is increased dose-dependently in both sexes. Histopathologically, renal changes in the 500 and 1000 mg/kg groups consist of proximal tubular degeneration, juxtaglomerular cell hyperplasia and interstitial cell infiltration. Similar, but mild, changes in proximal tubules are present in the female 125 mg/kg group. Dead animals from the highest dose groups further show gastrointestinal hemorrhagic erosion and/or ulcer, decrease bone marrow erythropoiesis and hepatocytic vacuolar degeneration. There is no pathological alteration in rats from other Rentiapril-treated groups, as well as in controls. These results indicate that the no-effect dose of Rentiapril in rats by three months oral administration is 30 mg/kg in female and 125 mg/kg in male[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

313.39

Formula

C13H15NO4S2
CAS 号
性状

固体

颜色

White to off-white

中文名称

伦唑普利外消旋体；伦噻普利外消旋体
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 100 mg/mL (319.09 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.1909 mL 15.9546 mL 31.9091 mL
5 mM 0.6382 mL 3.1909 mL 6.3818 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Rentiapril racemate 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1909 mL 15.9546 mL 31.9091 mL 79.7728 mL
5 mM 0.6382 mL 3.1909 mL 6.3818 mL 15.9546 mL
10 mM 0.3191 mL 1.5955 mL 3.1909 mL 7.9773 mL
15 mM 0.2127 mL 1.0636 mL 2.1273 mL 5.3182 mL
20 mM 0.1595 mL 0.7977 mL 1.5955 mL 3.9886 mL
25 mM 0.1276 mL 0.6382 mL 1.2764 mL 3.1909 mL
30 mM 0.1064 mL 0.5318 mL 1.0636 mL 2.6591 mL
40 mM 0.0798 mL 0.3989 mL 0.7977 mL 1.9943 mL
50 mM 0.0638 mL 0.3191 mL 0.6382 mL 1.5955 mL
60 mM 0.0532 mL 0.2659 mL 0.5318 mL 1.3295 mL
80 mM 0.0399 mL 0.1994 mL 0.3989 mL 0.9972 mL
100 mM 0.0319 mL 0.1595 mL 0.3191 mL 0.7977 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rentiapril72679-47-1SA-446伦唑普利外消旋体伦噻普利外消旋体SA446SA 446Angiotensin-converting Enzyme (ACE)Inhibitorinhibitorinhibit

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目录号：
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