1. PI3K/Akt/mTOR Stem Cell/Wnt MAPK/ERK Pathway
  2. GSK-3 p38 MAPK
  3. TCS 183

TCS 183 是一种多肽,是一种 GSK-3β 抑制剂。TCS 183 可以阻断 GSK-3β 的自身抑制并减少 AMPK 磷酸化水平。TCS 183 可用于神经病理疾病,尤其是阿尔茨海默病研究。

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Custom Peptide Synthesis

TCS 183

TCS 183 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TCS 183, a peptide, is a GSK-3β inhibitor. TCS 183 blocks GSK-3β autoinhibition and decreases the level of AMPK phosphorylation. TCS 183 can be used for neuropathological diseases, particularly Alzheimer’s disease, research[1].

IC50 & Target[1]

GSK-3β

 

分子量

1425.57

Formula

C58H96N20O20S

Sequence

Met-Ser-Gly-Arg-Pro-Arg-Thr-Thr-Ser-Phe-Ala-Glu-Ser-NH2

Sequence Shortening

MSGRPRTTSFAES-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
TCS 183
目录号:
HY-P1385
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