2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. HSP
  4. A17 peptide

A17 peptide 是一种 Hsp70 靶向肽。A17 peptide 与 Hsp70 的 ATP 结合域结合。A17 peptide 特异性抑制分子伴侣活性，从而增强细胞对化疗药物 (例如 Cisplatin (HY-17394)) 诱导的细胞凋亡的敏感性。A17 peptide 可用于抗癌化疗研究，例如多发性骨髓瘤。

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Custom Peptide Synthesis

A17 peptide

A17 peptide Chemical Structure

CAS No. : 1140483-31-3

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A17 peptide 相关抗体

Top Publications Citing Use of Products

查看 HSP 亚型特异性产品:

查看所有亚型
HSP40 HSP70 HSP90 HSP105 HSF1 HSP HSPA5

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

A17 peptide is a Hsp70-targeting peptide. A17 peptide binds to the ATP-binding domains of Hsp70. A17 peptide specifically inhibits the chaperone activity, thereby increasing the cells' sensitivity to apoptosis induced by chemotherapeutic agents, such as Cisplatin (HY-17394). A17 peptide can be used for anticancer chemotherapy research, such multiple myeloma[1].

IC50 & Target[1]

HSP70

 

分子量

1636.83

Formula

C76H105N19O20S
CAS 号
Sequence

Tyr-Cys-Ala-Tyr-Tyr-Ser-Pro-Arg-His-Lys-Thr-Thr-Phe
Sequence Shortening

YCAYYSPRHKTTF
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

A17 peptide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A17 peptide1140483-31-3HSPHeat shock proteinsTargeting peptideHsp70ATP-binding domainsApoptosisCisplatinB16F10 cellsAnticancer chemotherapyMultiple myelomaInhibitorinhibitorinhibit

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目录号：
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