2. Immunology/Inflammation
  3. Glycoprotein VI
  4. Anti-GPC-2 Antibody (CT3)

Anti-GPC-2 Antibody (CT3) 

目录号: HY-P990842
技术支持

Anti-GPC-2 Antibody (CT3) 是一种小鼠 IgG1 κ 嵌合抗体，靶向人 GPC-2。Anti-GPC-2 Antibody (CT3) 与糖蛋白-2 (GPC2) 的肿瘤相关外显子 3 和 10 发生反应。Anti-GPC-2 Antibody (CT3) 可用于癌症的研究，如神经母细胞瘤。

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Anti-GPC-2 Antibody (CT3)

Anti-GPC-2 Antibody (CT3) Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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5 mg   询价  
10 mg   询价  

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Anti-GPC-2 Antibody (CT3) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-GPC-2 Antibody (CT3) is a kind of mouse IgG1 κ chimeric antibody, targeting to human GPC-2. Anti-GPC-2 Antibody (CT3) reacts with tumor-associated exons 3 and 10 of glypicans-2 (GPC2). Anti-GPC-2 Antibody (CT3) can be used for the research of cancer, such as neuroblastoma[1].

同型

Mouse IgG1 kappa
反应种属

Human
IC50 & Target

GPC-2
体外研究
(In Vitro)

Anti-GPC-2 Antibody (CT3) (1 μg/mL) 可与 GPC2 的肿瘤相关外显子 3 和 10 结合[1]。
Anti-GPC-2 Antibody (CT3) (携带 CT3 单链可变片段 (scFv) 的 CAR-T 细胞) (24 h) 可杀死近 70% 的 GPC2 过表达 A431 和 IMR5 细胞[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-GPC-2 Antibody (CT3) 相关抗体:
体内研究
(In Vivo)

Anti-GPC-2 Antibody (CT3) (携带 CT3 单链可变片段 (scFv) 的 CAR-T 细胞) (10 M，静脉注射) 可使负荷 IMR5 肿瘤 NSG 小鼠的肿瘤消退并延长其生存期[1]。
Anti-GPC-2 Antibody (CT3) (携带 CT3 单链可变片段 (scFv) 的 CAR-T 细胞) (2 M，静脉注射) 可使负荷 NBEB 肿瘤 NSG 小鼠的肿瘤消退并延长其生存期[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: IMR5 tumor mice (5-week, female, NSG mice)[1]
Dosage: 10 M (CAR T cells harboring the single-chain variable fragment (scFv) of the CT3)
Administration: Intravenously injection
Result: Led to a reduction in tumor size and suppressed tumor growth.
Prolonged survival of mice.
基因 ID

71951  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-GPC-2 Antibody (CT3) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-GPC-2 Antibody (CT3)Glycoprotein VIGPVIGPC-2NeuroblastomaA431IMR5NBEBInhibitorinhibitorinhibit

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