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  4. Anti-Mouse CD11a Antibody (FD441.8)

Anti-Mouse CD11a Antibody (FD441.8) 

目录号: HY-P99120 纯度: 95.00%
COA 技术支持

Anti-Mouse CD11a Antibody (FD441.8) 是一种抗小鼠 CD11a 的 IgG2b 抗体抑制剂，来源于大鼠宿主。Anti-Mouse CD11a Antibody (FD441.8) 能够中和 CD11a (也称为 LFA-1α，即淋巴细胞功能相关抗原 1α)。Anti-Mouse CD11a Antibody (FD441.8) 可用于炎症、免疫学和癌症等领域的研究，如移植和白血病。

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Anti-Mouse CD11a Antibody (FD441.8)

Anti-Mouse CD11a Antibody (FD441.8) Chemical Structure

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10 mg ￥10500
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Anti-Mouse CD11a Antibody (FD441.8) 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD11a Antibody (FD441.8) is an anti-mouse CD11a IgG2b antibody inhibitor derived from the host Rat. Anti-Mouse CD11a Antibody (FD441.8) can neutralize CD11a also known as LFA-1α (lymphocyte function-associated antigen 1 alpha). Anti-Mouse CD11a Antibody (FD441.8) can be used for the researches of inflammation, immunology and cancer, such as transplant and leukemia[1][2][3].

同型

Rat IgG2b kappa
推荐同型对照抗体
反应种属

Mouse
IC50 & Target

CD11a
体内研究
(In Vivo)

Anti-Mouse CD11a Antibody (FD441.8) (31.25 μg，腹腔注射，从移植前一天开始每 3 天一次) 可延长大鼠胰岛异种移植的小鼠中移植物存活时间并提高接受率[1]。
Anti-Mouse CD11a Antibody (FD441.8) (300 μg，静脉注射，在半抗原攻击当天) 可抑制二硝基氟苯 (DNFB) 致敏的野生型小鼠中 CXCL1 的产生[2]。
Anti-Mouse CD11a Antibody (FD441.8) (用 50 μg/mL 的 FD441.8 预处理 30 分钟 的 T 细胞) 可增强小鼠的肺迁出和向骨髓的转运[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: DNFB sensitized wild-type mice[2]
Dosage: 300 μg
Administration: Intravenously injection, at day of hapten-challenge
Result: Inhibited CXCL1 production.
Attenuated or absent neutrophil infiltration.
基因 ID

16408  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-Mouse CD11a Antibody (FD441.8) 相关分类

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD11a Antibody (FD441.8)IntegrinCD11aLFA-1αTransplantLeukemiaCXCL1Inhibitorinhibitorinhibit

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