1. Immunology/Inflammation
  2. Fc Receptor (FcR)
  3. Anti-Mouse CD16.2 Antibody (9E9)

Anti-Mouse CD16.2 Antibody (9E9) 

目录号: HY-P990291
技术支持

Anti-Mouse CD16.2 Antibody (9E9) 是一种源自亚美尼亚仓鼠的 IgG 型抗体抑制剂,靶向小鼠 CD16.2。Anti-Mouse CD16.2 Antibody (9E9) 与小鼠 CD16.2 发生反应, 也被称为 FcγRIV (Fc 受体,IgG,低亲和力 IV)。Anti-Mouse CD16.2 Antibody (9E9) 抑制细胞 CD16.2 的表达和信号传导,并阻断 FcγRIV。Anti-Mouse CD16.2 Antibody (9E9) 可用于癌症、炎症和免疫学研究,如 CT26 肿瘤和肺部炎症研究。

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Anti-Mouse CD16.2 Antibody (9E9)

Anti-Mouse CD16.2 Antibody (9E9) Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD16.2 Antibody (9E9) is a Armenian hamster-derived IgG type antibody inhibitor, targeting to mouse CD16.2. Anti-Mouse CD16.2 Antibody (9E9) reacts with mouse CD16.2, also known as FcγRIV (Fc receptor, IgG, low affinity IV). Anti-Mouse CD16.2 Antibody (9E9) inhibits cellular CD16.2 expression and signaling and blocks FcγRIV. Anti-Mouse CD16.2 Antibody (9E9) can be used for the researches of cancer, inflammation and immunology, such as CT26 tumor and lung inflammation[1][2][3].

同型

Armenian hamster IgG

推荐同型对照抗体
反应种属

Mouse

体外研究
(In Vitro)

Anti-Mouse CD16.2 Antibody (9E9) (10 μg/mL) 可消除 MH-S 细胞中 IgE 免疫复合物诱导的 TNF-α 分泌[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Anti-Mouse CD16.2 Antibody (9E9) (在收集硫代乙醇酸盐诱导的巨噬细胞前 1 天静脉注射) 可抑制 hFcεRITg 小鼠中巨噬细胞 25% 的 TNF-α 分泌[1]
Anti-Mouse CD16.2 Antibody (9E9) (200 μg,腹腔注射,在第 0、4、8 天给药) 可减轻大疱性类天疱疮小鼠的皮肤损伤[2]
Anti-Mouse CD16.2 Antibody (9E9) (200 μg,在注射抗 CTLA4 前 1 小时,静脉注射) 可防止 CT26 肿瘤小鼠中抗 CTLA4 介导的调节性 T 细胞耗竭[3]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

应用

ELISA, FACS, Functional assay, Research in vivo

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

150 kDa

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anti-Mouse CD16.2 Antibody (9E9)
目录号:
HY-P990291
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