1. Immunology/Inflammation
  2. Transmembrane Glycoprotein
  3. Anti-Mouse CD83 Antibody (Michel-17)

Anti-Mouse CD83 Antibody (Michel-17) 

目录号: HY-P990261
技术支持

Anti-Mouse CD83 Antibody (Michel-17) 是一种源自大鼠的 IgG1 κ 型抗体抑制剂,靶向小鼠 CD83。Anti-Mouse CD83 Antibody (Michel-17) 可阻断 CD83 并抑制 T 细胞增殖。Anti-Mouse CD83 Antibody (Michel-17) 可用于癌症和免疫学的研究,如实体瘤。

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Anti-Mouse CD83 Antibody (Michel-17)

Anti-Mouse CD83 Antibody (Michel-17) Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD83 Antibody (Michel-17) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse CD83. Anti-Mouse CD83 Antibody (Michel-17) can block CD83 and inhibit T cells proliferation. Anti-Mouse CD83 Antibody (Michel-17) can be used for the researches of cancer and immunology, such as solid tumor[1][2].

同型

Rat IgG1 kappa

推荐同型对照抗体
反应种属

Mouse

IC50 & Target

CD83

体外研究
(In Vitro)

Anti-Mouse CD83 Antibody (Michel-17) (10 μg/mL, 3 days) 可减少树突状细胞与 T 细胞共培养体系中 CD4 阳性 T 细胞的增殖[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Anti-Mouse CD83 Antibody (Michel-17) (200 μg/mouse,腹腔注射,每 3 天一次) 在接受低分割放疗/来那度胺 (Lenalidomide) (HY-A0003) 治疗的荷瘤小鼠中,与抗 CD70 和抗 CD86 联用时,会使原发性和继发性肿瘤控制情况恶化,并降低总体生存率[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

基因 ID

12522  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

150 kDa

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anti-Mouse CD83 Antibody (Michel-17)
目录号:
HY-P990261
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