2. Immunology/Inflammation
  3. E-Selectin
  4. Anti-Mouse E-selectin/CD62E Antibody (9A9)

Anti-Mouse E-selectin/CD62E Antibody (9A9) 

目录号: HY-P990247 纯度: 95%
COA 技术支持

Anti-Mouse E-selectin/CD62E Antibody (9A9) 是一种抗小鼠 E-selectin/CD62E IgG2b 单克隆抗体。Anti-Mouse E-selectin/CD62E Antibody (9A9) 对癌细胞定植具有抑制作用。Anti-Mouse E-selectin/CD62E Antibody (9A9) 可用于研究炎症疾病和癌症，如急性微血管炎症和乳腺癌。

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Anti-Mouse E-selectin/CD62E Antibody (9A9)

Anti-Mouse E-selectin/CD62E Antibody (9A9) Chemical Structure

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1 mg ￥2200
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Anti-Mouse E-selectin/CD62E Antibody (9A9) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse E-selectin/CD62E Antibody (9A9) is an anti-mouse E-selectin/CD62E IgG2b monoclonal antibody. Anti-Mouse E-selectin/CD62E Antibody (9A9) has an inhibitory effect on cancer cell colonization. Anti-Mouse E-selectin/CD62E Antibody (9A9) can be used for researches on inflammation conditions and cancer such as acute microvascular inflammation and breast cancer[1][2].

同型

Rat IgG1 kappa
推荐同型对照抗体
反应种属

Mouse
IC50 & Target

E-selectin/CD62E
体内研究
(In Vivo)

Anti-Mouse E-selectin/CD62E Antibody (9A9) (30 μg，单次剂量) 显著增加了急性微血管炎症模型 C57BL/6 小鼠白细胞的滚动速度[1]。
Anti-Mouse E-selectin/CD62E Antibody (9A9) (10 mg/kg，静脉注射，单剂量) 显著减少了携带 E0771 肿瘤的 C57BL/6 小鼠中癌症细胞的早期肺定植[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 2.5×105 E0771 cells injected C57BL/6 mice (8-14 weeks)[2]
Dosage: 10 mg/kg
Administration: Intravenous injection (i.v.), single dose
Result: Significantly reduced early lung colonization of cancer cells in mice.
基因 ID

20339  [NCBI]

Accession

NP_035475.1
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-Mouse E-selectin/CD62E Antibody (9A9) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse E-selectin/CD62E Antibody (9A9)E-SelectinCD62EELAM1LECAM-2E-selectin/CD62EE0771microvascularInhibitorinhibitorinhibit

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Anti-Mouse E-selectin/CD62E Antibody (9A9)
目录号：
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