1. Immunology/Inflammation
  2. Transmembrane Glycoprotein
  3. Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1)

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) 

目录号: HY-P990157 纯度: 95.00%
COA 技术支持

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) 是一种抗小鼠 Thy1/CD90 IgG2a 单克隆抗体。Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) 可以清除脾脏和骨髓中的 T 细胞。Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) 可用于免疫学和炎症疾病的研究,如结肠炎。

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Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1)

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) Chemical Structure

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1 mg ¥2200
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) is an anti-mouse Thy1/CD90 IgG2a monoclonal antibody. Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) can clear T cells from the spleen and bone marrow. Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) can be used for researches on immunology and inflammation conditions such as colitis[1][2][3].

同型

Rat IgG2a kappa

推荐同型对照抗体
反应种属

Mouse

IC50 & Target

Thy1/CD90

体外研究
(In Vitro)

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) (50 μg/mL,1 小时) 与 1:20 兔补体联合使用可以清除小鼠脾脏中抗原呈递细胞 (APCs) 中的 T 细胞[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) (250 μg,腹腔注射,在 -1、1 和 4 天) 显著降低了 Rag2-/-Il2rg-/- 小鼠结肠炎的严重程度[3]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: CD40 mAb induced Rag2−/−Il2rg−/− mice (8-16 weeks)[3]
Dosage: 250 μg
Administration: Intraperitoneal injection (i.p.), on days −1, 1 and 4
Result: Cleared innate lymphocytes (including NKR LTi cells, LTi like cells, and NK cells).
Relieved colitis symptoms.
基因 ID

21838  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

纯度: 95.00%

参考文献

Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1)
目录号:
HY-P990157
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