2. Inhibitory Antibodies
  3. Bifikafusp alfa

Bifikafusp alfa  (Synonyms: L19-IL2)

目录号: HY-P99479

摩尔计算器

Bifikafusp alfa (L19-IL2) 是一种免疫研究融合蛋白，由与人细胞因子白细胞介素2 (IL2) 融合的人 L19 抗体组成。Bifikafusp alfa 对纤连蛋白的 EDB 域具有特异性。Bifikafusp alfa 具有抗癌活性。

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Bifikafusp alfa Chemical Structure

Bifikafusp alfa Chemical Structure

CAS No. : 1957239-90-5

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Bifikafusp alfa 相关抗体

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生物活性

Bifikafusp alfa (L19-IL2) is an immunoresearch fusion protein consisting of human L19 antibodies fused to the human cytokine interleukin 2 (IL2).Bifikafusp alfa is specific to the EDB domain of fibronectin. Bifikafusp alfa has anticancer activity[1].

体内研究
(In Vivo)

Bifikafusp alfa (1.43 and 4.29 MIU/kg; i.p.; daily; for 10 days; 雌性 NMRI 裸鼠 MiaPaca-A2 异种移植) 对已建立的胰腺癌具有抗肿瘤活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female NMRI nude mice with MiaPaca-A2 xenografts[1]
Dosage: 1.43 and 4.29 MIU/kg
Administration: Intraperitoneal injection; daily; for 10 days
Result: Reduced tumor volume to 21.4% (1.43 MIU/kg) and 2.7% (4.29 MIU/kg) compared with control mice.
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Keywords:

Bifikafusp alfa1957239-90-5L19-IL2Othersfusion proteinL19IL2EDB domainanticancerInhibitorinhibitorinhibit

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