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  3. Bonducellpin D

Bonducellpin D 

目录号: HY-N2949 纯度: >98.0%
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Bonducellpin D 是一种从 Caesalpinia minax 中分离出来呋喃二萜类内酯。 Bonducellpin D 表现出对 SARS-CoV MproMERS-CoV Mpro 的广谱抑制能力,Ki 值分别为 467.11 和 284.86 nM。Bonducellpin D 在体外表现出中等的抗癌活性。

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Bonducellpin D Chemical Structure

Bonducellpin D Chemical Structure

CAS No. : 197781-85-4

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Description

Bonducellpin D is a furanoditerpenoid lactone isolated from Caesalpinia minax. Bonducellpin D exhibits broad-spectrum inhibition potential against SARS-CoV Mpro and MERS-CoV Mpro, with an Ki of 467.11 and 284.86 nM, respectively. Bonducellpin D also exhibits moderate anti-cancer activity in vitro[1][2][3].

IC50 & Target

Ki: 467.11 nM (SARS-CoV Mpro), 284.86 nM (MERS-CoV Mpro)[1]

Molecular Weight

404.45

Formula

C₂₂H₂₈O₇

CAS No.

197781-85-4

SMILES

O[C@]([C@H]1OC(C)=O)(C(C)(CC2)C)[C@@]([C@](CC(OC=C3)=C3[C@]45[H])([H])[C@@]4([H])[C@@]1([H])OC5=O)([C@H]2O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Bonducellpin DSARS-CoVSARS coronavirusfuranoditerpenoidlactoneCaesalpiniaminaxMERS-CoVanti-cancerInhibitorinhibitorinhibit

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Bonducellpin D
目录号:
HY-N2949
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