1. Others Cell Cycle/DNA Damage Antibody-drug Conjugate/ADC Related Epigenetics Anti-infection Apoptosis
  2. Reference Standards Topoisomerase ADC Cytotoxin MicroRNA Influenza Virus Apoptosis Fungal Antibiotic
  3. Camptothecin (Standard)

Camptothecin (Standard)  (Synonyms: 喜树碱 (标准品); Campathecin (Standard); (S)-(+)-Camptothecin (Standard); CPT (Standard))

目录号: HY-16560R 纯度: ≥98%
产品使用指南 技术支持

Camptothecin (Standard) (Campathecin (Standard)) 是 Camptothecin (HY-16560) 的分析标准品。本产品用于研究及分析应用。Camptothecin (CPT),一种生物碱,是一种 DNA topoisomerase I (Topo I) 抑制剂,其 IC50 值为 679 nM。Camptothecin (CPT) 对结直肠癌、乳腺癌、肺癌和卵巢癌具有强大的抗肿瘤活性,通过改变人类癌细胞中的 miRNA 表达模式来调节 hypoxia-inducible factor-1α (HIF-1α) 活性。

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Camptothecin (Standard) Chemical Structure

Camptothecin (Standard) Chemical Structure

CAS No. : 7689-03-4

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生物活性

Camptothecin (Standard) (Campathecin (Standard)) is the analytical standard of Camptothecin (HY-16560). This product is intended for research and analytical applications. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells.

分子量

348.36

同用名

喜树碱 (标准品); Campathecin (Standard); (S)-(+)-Camptothecin (Standard); CPT (Standard)

Formula

C20H16N2O4

CAS 号
中文名称

喜树碱 (标准品)

结构分类
初始来源
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Camptothecin (Standard)
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