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  4. CRT0063465

CRT0063465 是人类 PGK1 和Stress Sensor DJ1 的配体，Kd 值为 24 μM (PGK1)。CRT0063465 调控端粒蛋白复合体的形成和端粒长度。

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CRT0063465 Chemical Structure

CRT0063465 Chemical Structure

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CRT0063465 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CRT0063465 is a Ligand of HumanPGK1andStress Sensor DJ1, with theKdof 24 μM ofPGK1. CRT0063465 modulates the shelterin complex composition and telomere Length[1].

体内研究
(In Vivo)

CRT0063465 (10, 100 nM，最长 84 天) 阻断低血糖 TCT116 细胞的端粒缩短[1]。
CRT0063465 (10 nM, 1周) 调节非应激条件下 HCT116 细胞中庇护蛋白复合物的组成[1]。
CRT0063465 (100 nM, 长达 100 h) 对 Bleomycin (HY-17565) 诱导的 A2780 细胞毒性具有保护作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

374.23

Formula

C17H16BrN3O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CRT0063465 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CRT0063465CRT 0063465CRT-0063465OthersTelomereCell agingTCT116A2780Glycolytic kinaseOxidative stress sensorInhibitorinhibitorinhibit

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产品名称：
CRT0063465
目录号：
HY-153917
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