1. Peptides
  2. Cyclic MKEY TFA

Cyclic MKEY TFA 是 CXCL4-CCL5 异二聚体形成的合成环肽抑制剂,其通过介导炎症来防止动脉粥样硬化和主动脉瘤形成。Cyclic MKEY TFA 还可以预防小鼠中风引起的脑损伤。

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Cyclic MKEY TFA Chemical Structure

Cyclic MKEY TFA Chemical Structure

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规格 价格 是否有货 数量
1 mg ¥500
In-stock
5 mg ¥1500
In-stock
10 mg ¥2400
In-stock
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100 mg   询价  

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Other Forms of Cyclic MKEY TFA:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cyclic MKEY TFA is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, which protects against atherosclerosis and aortic aneurysm formation by mediating inflammation. Cyclic MKEY TFA also protects against stroke-induced brain injury in mice[1][2].

IC50 & Target

CXCL4-CCL5[1]

分子量

2530.87 (free acide)

Formula

C113H174N28O34S2.xC2HF3O2

性状

固体

颜色

White to off-white

Sequence

Cys-Lys-Glu-Tyr-Phe-Tyr-Thr-Ser-Ser-Lys-Ser-Ser-Asn-Leu-Ala-Val-Val-Phe-Val-Thr-Arg-Cys (Disulfide bridge:Cys1-Cys22)

Sequence Shortening

CKEYFYTSSKSSNLAVVFVTRC (Disulfide bridge:Cys1-Cys22)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Cyclic MKEY TFA
目录号:
HY-P1949A
需求量: