1. Others Anti-infection
  2. Isotope-Labeled Compounds HCV
  3. Daclatasvir-d6

Daclatasvir-d6  (Synonyms: 达拉他韦-d6; BMS-790052-d6; EBP 883-d6)

目录号: HY-10466S
产品使用指南

Daclatasvir-d6 是 Daclatasvir 氘代物。Daclatasvir (BMS-790052) 是一种有效的口服活性 HCV NS5A 蛋白抑制剂,多种 HCV 复制子基因型的 EC50 范围为 9-146 pM。Daclatasvir 也是有机阴离子转运多肽 1B (OATP1B) 和 OATP1B3 抑制剂,IC50 分别为 1.5 µM 和 3.27 µM。

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Daclatasvir-d<sub>6</sub> Chemical Structure

Daclatasvir-d6 Chemical Structure

CAS No. : 1801709-41-0

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规格 价格 是否有货 数量
500 μg ¥5000
3 - 4 周
1 mg ¥7200
3 - 4 周
5 mg   询价  
10 mg   询价  

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Customer Review

Other Forms of Daclatasvir-d6:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Daclatasvir-d6 is deuterium labeled Daclatasvir. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively[1][2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

744.91

Formula

C40H44D6N8O6

CAS 号
非标记 CAS

2238824-44-5

中文名称

达卡他韦-d6;达拉他韦-d6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Daclatasvir-d6
目录号:
HY-10466S
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