2. Neuronal Signaling
  3. Cholinesterase (ChE) Monoamine Oxidase
  4. Desoxypeganine

Desoxypeganine  (Synonyms: Deoxypeganine; Deoxyvasicine)

目录号: HY-108048
产品使用指南

摩尔计算器

Desoxypeganine (Deoxypeganine) 是一种生物碱，是一种口服有效的胆碱酯酶 (BChE 和 AChE) 和选择性 MAO-A 抑制剂，其 IC50 值分别为 2、17 和 2 μM。 Desoxypeganine 可用于酒精滥用研究。

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Desoxypeganine Chemical Structure

Desoxypeganine Chemical Structure

CAS No. : 495-59-0

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Desoxypeganine 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

查看 Monoamine Oxidase 亚型特异性产品:

查看所有亚型
MAO-A MAO-B

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Desoxypeganine (Deoxypeganine), an alkaloid, is a potent and orally active cholinesterase (BChE and AChE) and selective MAO-A inhibitor, with IC50 values of 2, 17, and 2 μM, respectively. Desoxypeganine can be used for alcohol abuse research[1].

IC50 & Target

BChE

2 μM (IC50)

AChE

17 μM (IC50)

MAO-A

2 μM (IC50)

体内研究
(In Vivo)

Desoxypeganine (10-30 mg/kg，灌胃，每天一次，连续 16 天) 剂量依赖性地降低乙醇摄入量和乙醇偏好[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female Alko alcohol (AA) rats (Thirty eight adult)[1]
Dosage: 10, 20, 30 mg/kg
Administration: Gavage, once daily in a volume of 10 ml/kg at 6:00 pm, for 16 days
Result: Abolished ethanol preference.
分子量

172.23

Formula

C11H12N2
CAS 号
中文名称

化合物DESOXYPEGANINE
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Desoxypeganine 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Desoxypeganine495-59-0Deoxypeganine Deoxyvasicine化合物DESOXYPEGANINECholinesterase (ChE)Monoamine OxidaseMAOPeganum harmala L.butyrylcholinesteraseacetylcholinesteraseAlko alcoholalcohol abuseInhibitorinhibitorinhibit

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