Dimephosphon 

Dimephosphon is an anti-inflammatory agent with antihistamine and antiserotonin activities. Dimephosphon helps maintain the conduction function of the spinal cord and reduces the excitability of spinal motor neurons in the area surrounding the lesion. Dimephosphon directly activates lymphatic vessel movement and improves lymphatic circulation. Dimephosphon can be used for the study of inflammatory edema, acute spinal cord injury and lymphatic circulation disorders^[1][2][3].

Dimephosphin 的抗组胺和抗血清素活性已在足底注射炎症介质和调节剂引起的爪水肿模型中得到证实^[1]。
Dimephosphin (2.5% Dimephosphin 溶液，1 mL，每日一次，连续 10 天) 可促进脊髓损伤杂种犬脊髓传导功能的恢复，其机制可能与抗水肿、血管保护和降低神经元过度兴奋有关^[2]。
Dimephosphin (50 mg/kg，腹腔注射，一次给药) 通过直接激活大鼠淋巴管收缩 (刺激管壁和瓣膜肌细胞) 来增强淋巴循环^[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

208.19

C₈H₁₇O₄P

14394-26-4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Ziganshina LE, et al. [Effect of dimephosphon on the inflammatory reaction]. Farmakol Toksikol. 1988 May-Jun;51(3):58-60.  [Content Brief]

  [2]. A M Eremeev, et al. Effect of Dimephosphon on Functional Recovery of Damaged Spinal Cord. Bull Exp Biol Med. 2006 Feb;141(2):181-3.  [Content Brief]

  [3]. R Kh Khafiz'yanova, et al. Lymphotropic Effect of Dimephosphon, Mexidol, and Ketorolac is Realized via Activation of the Lymphangion and Stimulation of Lymph Formation. Bull Exp Biol Med. doi: 10.1007/s10517-007-0152-5.  [Content Brief]