1. Others Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds 5 alpha Reductase
  3. Finasteride-d9

Finasteride-d9  (Synonyms: 非那雄胺-d9; MK-906-d9)

目录号: HY-13635S
产品使用指南

Finasteride-d9 是 Finasteride 氘代物。Finasteride (MK-906) 是一种有效的竞争性 5α-还原酶 (5α-reductase) 抑制剂,对 II 型 5α-还原酶的 IC50 值为 4.2 nM。Finasteride 对 II 型 5α-还原酶的亲和力比对 I 型酶高约 100 倍。Finasteride 可用于研究前列腺增生 (BPH) 和雄激素性脱发。

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Finasteride-d<sub>9</sub> Chemical Structure

Finasteride-d9 Chemical Structure

CAS No. : 1131342-85-2

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规格 价格 是否有货 数量
5 mg
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1 mg ¥5634
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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Finasteride-d9 is deuterium labeled Finasteride. Finasteride (MK-906) is a potent and competitive 5α-reductase inhibitor, with an IC50 of 4.2 nM for type II 5α-reductase. Finasteride has approximately a 100-fold greater affinity for type II 5α-reductase enzyme than for the type I enzyme. Finasteride can be used for the research of benign prostatic hyperplasia (BPH) and androgenic alopecia[1][2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

381.60

Formula

C23H27D9N2O2

CAS 号
中文名称

非那雄胺-d9;非那斯特萊-d9;非那司提-d9;非那甾胺-d9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
HY-13635S
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