2. Metabolic Enzyme/Protease
  3. MMP
  4. FN-439

FN-439 是一种选择性胶原酶 1 抑制剂。FN-439 抑制胶原酶-1，IC50 值为 1 μM。FN-439 可用于癌症和炎症的研究。

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Custom Peptide Synthesis

FN-439 Chemical Structure

FN-439 Chemical Structure

CAS No. : 124168-73-6

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规格 是否有货
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FN-439 的其他形式现货产品:

Customer Review

Other Forms of FN-439:

FN-439 相关抗体

Top Publications Citing Use of Products

查看 MMP 亚型特异性产品:

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MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FN-439 is a selective collagenase-1 inhibitor. FN-439 inhibits collagenase-1 with an IC50 value of 1 μM. FN-439 can be used for the research of cancer and inflammation[1][2].

体外研究
(In Vitro)

FN-439 inhibits collagenase-1 with an IC50 value of 1 μM[1].
FN-439 (1 μM) reduces the invasive potential of MDA-MB-231 breast cancer cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

FN-439 相关抗体:
体内研究
(In Vivo)

FN-439 significantly decreases neutrophils and macrophages, shows extensive bone formation and active cementogenesis in the periapical region when has a combination with ofloxaci[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

490.55

Formula

C23H34N6O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FN-439 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FN-439124168-73-6FN439FN 439MMPMatrix metalloproteinasescollagenase-1cancerinflammationapical periodontitiscollagenaseInhibitorinhibitorinhibit

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目录号：
HY-100210
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