2. Gene
  3. Orai1 - ORAI calcium release-activated calcium modulator 1 Gene

Orai1 - ORAI calcium release-activated calcium modulator 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: orai-1; Tmem142a; D730049H07Rik

基因 ID: 109305 | 基因类型: protein coding

关于 Orai1

功能概要

Predicted to enable identical protein binding activity and store-operated Calcium Channel activity. Acts upstream of or within calcium ion import; mammary gland epithelium development; and store-operated calcium entry. Located in basolateral plasma membrane. Part of protein-containing complex. Is expressed in several structures, including alimentary system; brain; reproductive system; respiratory system; and skin. Human ortholog(s) of this gene implicated in immunodeficiency 9 and tubular aggregate myopathy 2. Orthologous to human ORAI1 (ORAI calcium release-activated calcium modulator 1). [provided by Alliance of Genome Resources, Apr 2022]

Orai1 基因产物(1)

mRNA Protein Name
NM_175423.3 NP_780632.1 calcium release-activated calcium channel protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17343823 MGI
enables store-operated calcium channel activity IMP
IMP: 通过突变表型推断
31664108 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within calcium ion import IDA
IDA: 通过直接分析推断
23840669 MGI
involved in ion channel modulating, G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
31664108 MGI
involved in ligand-gated ion channel signaling pathway IMP
IMP: 通过突变表型推断
31664108 MGI
acts upstream of or within mammary gland epithelium development IMP
IMP: 通过突变表型推断
23840669 MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
31664108 MGI
involved in positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
31664108 MGI
acts upstream of or within store-operated calcium entry IGI
IGI: 通过遗传相互作用推断
17343823 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
23840669 MGI
located in membrane IDA
IDA: 通过直接分析推断
17343823 MGI
is active in plasma membrane IDA
IDA: 通过直接分析推断
17343823 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calcium release-activated calcium channel protein 1

calcium release-activated calcium channel 1

protein orai-1

transmembrane protein 142A

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-101942 Zegocractin Inhibitor 99.96% Phase 2
Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19408 Pyr10 Inhibitor 99.95% 否
HY-103310 MRS1845 Inhibitor 99.46% 否
HY-113618B RO2959 monohydrochloride Inhibitor 98.19% 否
HY-12521 GSK-5498A Inhibitor 99.94% 否
HY-113618A RO2959 hydrochloride Inhibitor / 否
HY-RS17989 Orai1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-103071 GSK-5503A Inhibitor / 否
HY-RS09822 ORAI1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24460 Orai1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990478 Anti-Orai1 Antibody / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Orai1 NCBI NCBI:84876
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z