2. Gene
  3. Rap1a - RAS-related protein 1a Gene

Rap1a - RAS-related protein 1a Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Rap1; G-22K; Krev-1

基因 ID: 109905 | 基因类型: protein coding

关于 Rap1a

功能概要

Enables GTPase activity and small GTPase binding activity. Involved in positive regulation of vasculogenesis. Acts upstream of or within several processes, including negative regulation of synaptic vesicle exocytosis; positive regulation of ERK1 and ERK2 cascade; and positive regulation of neuron projection development. Located in several cellular components, including cell junction; neuron projection; and plasma membrane. Part of guanyl-nucleotide exchange factor complex. Is expressed in brain; early conceptus; hemolymphoid system gland; and oocyte. Orthologous to human RAP1A (RAP1A, member of Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rap1a 基因产物(1)

mRNA Protein Name
NM_145541.5 NP_663516.1 ras-related protein Rap-1A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase activity IDA
IDA: 通过直接分析推断
12473665 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
14712229 MGI
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
15894621 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of synaptic vesicle exocytosis IGI
IGI: 通过遗传相互作用推断
23616533 MGI
acts upstream of or within positive regulation of ERK1 and ERK2 cascade IGI
IGI: 通过遗传相互作用推断
23616533 MGI
acts upstream of or within positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
22732430 MGI
involved in positive regulation of vasculogenesis IMP
IMP: 通过突变表型推断
19635461 MGI
acts upstream of or within small GTPase-mediated signal transduction IDA
IDA: 通过直接分析推断
12473665 MGI
acts upstream of synaptic vesicle exocytosis IGI
IGI: 通过遗传相互作用推断
23616533 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell junction IDA
IDA: 通过直接分析推断
19635461 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
22732430 MGI
part of guanyl-nucleotide exchange factor complex IDA
IDA: 通过直接分析推断
15894621 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
22732430 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
17403904 MGI
located in sperm midpiece IDA
IDA: 通过直接分析推断
30360518 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ras-related protein Rap-1A

GTP-binding protein SMG-P21A

ras-related protein Krev-1

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15871 GGTI298 Trifluoroacetate Inducer 99.87% 否
HY-123242 FTI-2153 Inhibitor 99.11% 否
HY-12369 GGTI-2133 Inhibitor 98.50% 否
HY-100876 GGTI298 Inducer / 否
HY-115489A GGTI-286 TFA Inhibitor / 否
HY-123242A FTI-2153 TFA Inhibitor 99.11% 否
HY-115489 GGTI-286 Inhibitor / 否
HY-117935 GGTI-286 hydrochloride Inhibitor / 否
HY-RS16300 Rap1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-120229 GGTI-2147 Inhibitor / 否
HY-12369A GGTI-2133 TFA Inhibitor / 否
HY-RS11652 RAP1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-120271 GGTI-297 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rap1a NCBI NCBI:5906
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