1. Gene
  2. Acr - acrosin prepropeptide Gene

Acr - acrosin prepropeptide Gene

种属: Mus musculus

基因 ID: 11434 | 基因类型: protein coding

关于 Acr

功能概要

Enables peptidase activity. Involved in single fertilization. Acts upstream of or within binding activity of sperm to zona pellucida and penetration of zona pellucida. Located in acrosomal vesicle. Is expressed in testis. Orthologous to human ACR (acrosin). [provided by Alliance of Genome Resources, Apr 2022]

Acr 基因产物(7)

mRNA Protein Name
NM_001205049.2 NP_001191978.1 acrosin isoform 2 precursor
NM_001277245.2 NP_001264174.1 acrosin isoform 3
NM_001277246.2 NP_001264175.1 acrosin isoform 3
NM_001277247.2 NP_001264176.1 acrosin isoform 4 precursor
NM_001411168.1 NP_001398097.1 acrosin isoform 5 precursor
NM_001411169.1 NP_001398098.1 acrosin isoform 3
NM_013455.4 NP_038483.1 acrosin isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptidase activity IMP
IMP: 通过突变表型推断
7989357 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11739644 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within binding of sperm to zona pellucida IGI
IGI: 通过遗传相互作用推断
15685642 MGI
acts upstream of or within penetration of zona pellucida IGI
IGI: 通过遗传相互作用推断
15051954 MGI
acts upstream of or within penetration of zona pellucida IMP
IMP: 通过突变表型推断
7989357 MGI
involved in single fertilization IMP
IMP: 通过突变表型推断
15685642 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in acrosomal vesicle IDA
IDA: 通过直接分析推断
7798216 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

acrosin

preproacrosin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Acr NCBI NCBI:49
Canis familiaris Acr NCBI NCBI:606765
Macaca fascicularis Acr NCBI NCBI:102115325
Rattus norvegicus Acr NCBI NCBI:24163
Macaca mulatta Acr NCBI NCBI:716579