2. Gene
  3. Eif4ebp1 - eukaryotic translation initiation factor 4E binding protein 1 Gene

Eif4ebp1 - eukaryotic translation initiation factor 4E binding protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: PHAS-I

基因 ID: 116636 | 基因类型: protein coding

关于 Eif4ebp1

功能概要

Enables eukaryotic initiation factor 4E binding activity and protein Phosphatase 2A binding activity. Involved in several processes, including response to amino acid starvation; response to ethanol; and response to ischemia. Located in cytoplasm and nucleus. Part of protein-containing complex. Is active in glutamatergic synapse and postsynaptic cytosol. Used to study tuberous sclerosis. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human EIF4EBP1 (eukaryotic translation initiation factor 4E binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Eif4ebp1 基因产物(1)

mRNA Protein Name
NM_053857.2 NP_446309.1 eukaryotic translation initiation factor 4E-binding protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables eukaryotic initiation factor 4E binding IPI
IPI: 通过物理相互作用推断
18952566 RGD
enables protein phosphatase 2A binding IPI
IPI: 通过物理相互作用推断
16899564 RGD
enables translation initiation factor binding IPI
IPI: 通过物理相互作用推断
11865047 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hypoxia IDA
IDA: 通过直接分析推断
10100614 RGD
involved in lung development IEP
IEP: 通过表达模式推断
18952566 RGD
involved in negative regulation of protein-containing complex assembly IMP
IMP: 通过突变表型推断
11865047 RGD
involved in negative regulation of translational initiation IMP
IMP: 通过突变表型推断
11865047 RGD
involved in response to amino acid starvation IDA
IDA: 通过直接分析推断
11500297 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
15388509 RGD
involved in response to ischemia IEP
IEP: 通过表达模式推断
20736160 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
11756682 RGD
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
11756682 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
18952566 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

eukaryotic translation initiation factor 4E-binding protein 1

4E-BP1

eIF4E-binding protein 1

phosphorylated heat- and acid-stable protein regulated by insulin 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04277 EIF4EBP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20227 Eif4ebp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26734 Eif4ebp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eif4ebp1 NCBI NCBI:1978
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