2. Gene
  3. Bmp6 - bone morphogenetic protein 6 Gene

Bmp6 - bone morphogenetic protein 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Vgr1; D13Wsu115e

基因 ID: 12161 | 基因类型: protein coding

关于 Bmp6

功能概要

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of Smad Family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Mice lacking this gene exhibit delayed ossification of the sternum, iron overload, and reduced fertility in females. [provided by RefSeq, Jul 2016]

Bmp6 基因产物(1)

mRNA Protein Name
NM_007556.4 NP_031582.1 bone morphogenetic protein 6 preproprotein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12897139 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within BMP signaling pathway IDA
IDA: 通过直接分析推断
14623234 MGI
involved in cellular response to iron ion IMP
IMP: 通过突变表型推断
19252488 MGI
acts upstream of or within endochondral ossification IMP
IMP: 通过突变表型推断
9664685 MGI
involved in eye development IGI
IGI: 通过遗传相互作用推断
16154126 MGI
involved in inflammatory response IEP
IEP: 通过表达模式推断
12151307 MGI
acts upstream of or within intracellular iron ion homeostasis IMP
IMP: 通过突变表型推断
21703414 MGI
involved in intracellular iron ion homeostasis IMP
IMP: 通过突变表型推断
19252488 MGI
involved in kidney development IGI
IGI: 通过遗传相互作用推断
16154126 MGI
acts upstream of or within male genitalia development IGI
IGI: 通过遗传相互作用推断
9664685 MGI
involved in multicellular organismal-level iron ion homeostasis IMP
IMP: 通过突变表型推断
19252488 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19252488 MGI
acts upstream of or within neuron differentiation IMP
IMP: 通过突变表型推断
14623245 MGI
acts upstream of or within osteoblast differentiation IGI
IGI: 通过遗传相互作用推断
16109715 MGI
involved in positive regulation of SMAD protein signal transduction IMP
IMP: 通过突变表型推断
19252488 MGI
involved in positive regulation of endothelial cell differentiation IDA
IDA: 通过直接分析推断
20406889 MGI
involved in positive regulation of endothelial cell proliferation IDA
IDA: 通过直接分析推断
20406889 MGI
involved in positive regulation of lipopolysaccharide-mediated signaling pathway IMP
IMP: 通过突变表型推断
19252488 MGI
acts upstream of or within positive regulation of neuron differentiation IDA
IDA: 通过直接分析推断
9786991 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19252488 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

bone morphogenetic protein 6

VG-1-related protein

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16712 LDN-214117 Inhibitor 99.92% 否
HY-RS01541 BMP6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17946 Bmp6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24417 Bmp6 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990974 Bezeotermin alfa / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bmp6 NCBI NCBI:654
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