2. Gene
  3. Celsr1 - cadherin, EGF LAG seven-pass G-type receptor 1 Gene

Celsr1 - cadherin, EGF LAG seven-pass G-type receptor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Scy; Crsh; crash; Adgrc1

基因 ID: 12614 | 基因类型: protein coding

关于 Celsr1

功能概要

Predicted to enable calcium ion binding activity. Involved in establishment of planar polarity and neural tube closure. Acts upstream of or within several processes, including Rho protein signal transduction; apical protein localization; and morphogenesis of an epithelium. Located in membrane. Is expressed in several structures, including blastocyst; central nervous system; epithelium; primitive streak; and renal cortex. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human CELSR1 (Cadherin EGF LAG seven-pass G-type receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Celsr1 基因产物(1)

mRNA Protein Name
NM_009886.2 NP_034016.2 cadherin EGF LAG seven-pass G-type receptor 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18849982 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Rho protein signal transduction IMP
IMP: 通过突变表型推断
20223754 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: 通过突变表型推断
18849982 MGI
acts upstream of or within apical protein localization IMP
IMP: 通过突变表型推断
16687519 MGI
acts upstream of or within establishment of body hair planar orientation IMP
IMP: 通过突变表型推断
18849982 MGI
involved in establishment of planar polarity IMP
IMP: 通过突变表型推断
12842012 MGI
acts upstream of or within establishment of planar polarity of embryonic epithelium IMP
IMP: 通过突变表型推断
12842012 MGI
acts upstream of or within hair follicle development IMP
IMP: 通过突变表型推断
18849982 MGI
acts upstream of or within inner ear morphogenesis IMP
IMP: 通过突变表型推断
12842012 MGI
acts upstream of or within lateral sprouting involved in lung morphogenesis IMP
IMP: 通过突变表型推断
20223754 MGI
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
10932191 MGI
acts upstream of or within motor neuron migration IMP
IMP: 通过突变表型推断
20631168 MGI
acts upstream of or within neural tube closure IGI
IGI: 通过遗传相互作用推断
17229766 MGI
involved in neural tube closure IMP
IMP: 通过突变表型推断
12842012 MGI
acts upstream of or within orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis IMP
IMP: 通过突变表型推断
20223754 MGI
acts upstream of or within planar dichotomous subdivision of terminal units involved in lung branching morphogenesis IMP
IMP: 通过突变表型推断
20223754 MGI
acts upstream of or within protein localization involved in establishment of planar polarity IDA
IDA: 通过直接分析推断
18849982 MGI
acts upstream of or within regulation of actin cytoskeleton organization IMP
IMP: 通过突变表型推断
20223754 MGI
acts upstream of or within wound healing IGI
IGI: 通过遗传相互作用推断
20643356 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
20353824 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cadherin EGF LAG seven-pass G-type receptor 1

cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)

seven-pass transmembrane receptor

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-175232 GL64 / 否
HY-RS02465 CELSR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18558 Celsr1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25040 Celsr1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Celsr1 NCBI NCBI:9620
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